Fossil DNA
نویسنده
چکیده
Also known as... ancient DNA. The New Shorter Oxford Dictionary offers the precise explanation of ‘ancient’ as ‘belonging or pertaining to the period before the fall of the Western Roman Empire in AD 476.’ DNA can be recovered from fossils much older than 1500 years, but the inevitable time-dependent decay of the DNA structure due to oxidation and hydrolysis makes retrieval increasingly difficult with age.
منابع مشابه
Freshly excavated fossil bones are best for amplification of ancient DNA.
Despite the enormous potential of analyses of ancient DNA for phylogeographic studies of past populations, the impact these analyses, most of which are performed with fossil samples from natural history museum collections, has been limited to some extent by the inefficient recovery of ancient genetic material. Here we show that the standard storage conditions and/or treatments of fossil bones i...
متن کاملUltrastructure and DNA Sequence Analysis of Single Fossil Sediment Cells
The method we have developed allows the cytoplasm of a single fossil cell to be sufficiently preserved as to be distinguished by fluorescence microscopy. Analysis of fossil DNA involved PCR amplification of the spacer region between rrn5 and trnR genes in the chloroplast genome. The DNA and consensus sequences, obtained from the same PCR amplification fragment, were analysed by BLAST search and...
متن کاملPhylogeography of Douglas-fir based on mitochondrial and chloroplast DNA sequences: testing hypotheses from the fossil record.
The integration of fossil and molecular data can provide a synthetic understanding of the ecological and evolutionary history of an organism. We analysed range-wide maternally inherited mitochondrial DNA and paternally inherited chloroplast DNA sequence data with coalescent simulations and traditional population genetic methods to test hypotheses of population divergence generated from the foss...
متن کاملThe thermal history of human fossils and the likelihood of successful DNA amplification.
Recent success in the amplification of ancient DNA (aDNA) from fossil humans has led to calls for further tests to be carried out on similar material. However, there has been little systematic research on the survival of DNA in the fossil record, even though the environment of the fossil is known to be of paramount importance for the survival of biomolecules over archaeological and geological t...
متن کاملRelatively well preserved DNA is present in the crystal aggregates of fossil bones.
DNA from fossil human bones could provide invaluable information about population migrations, genetic relations between different groups and the spread of diseases. The use of ancient DNA from bones to study the genetics of past populations is, however, very often compromised by the altered and degraded state of preservation of the extracted material. The universally observed postmortem degrada...
متن کاملFossil avian eggshell preserves ancient DNA.
Owing to exceptional biomolecule preservation, fossil avian eggshell has been used extensively in geochronology and palaeodietary studies. Here, we show, to our knowledge, for the first time that fossil eggshell is a previously unrecognized source of ancient DNA (aDNA). We describe the successful isolation and amplification of DNA from fossil eggshell up to 19 ka old. aDNA was successfully char...
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ورودعنوان ژورنال:
- Current Biology
دوره 10 شماره
صفحات -
تاریخ انتشار 2000